The Emotional Growth 2 Study

*We are currently not recruiting for this study.*

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The goal of this study is to collect pilot data in order to add a group of preschool children exposed to opioids during pregnancy to our existing and ongoing EmoGrow study. The goal of the overall EmoGrow project is to launch an innovative, multi-modal neuroimaging program that will investigate the longitudinal trajectory of the neurodevelopment of irritability across the preschool period. Irritability exists on a dimension in every member of the population, however, it is also a significant mental health concern that is present in nearly every form of psychopathology and spans the internalizing/externalizing gap. Differentiating clinically salient irritability from developmentally-normative temperamental variation has proven to be a difficult task. This is made even more challenging during the preschool period, when irritability has hit its normative peak and measuring neurodevelopment is impeded by methodological constraints.

This state-of-the-art program of research will 1) identify specific biomarkers underlying preschool vulnerability for psychopathology by examining neural maturation in executive function as a predictor for clinical outcome and 2) examine how the parenting environment moderates this trajectories as the foundation for future brain-based behavioral intervention.